Improve health outcomes and accelerate research
Clinical-grade genetic results delivered through
an engaging participant experience
Get started Case study: Helix and Healthy Nevada
Powering the world’s fastest growing population health program in Nevada
Researchers at the Healthy Nevada Project had originally started with microarray data, but soon realized that they needed CLIA/CAP exome data to meet their goals. Our high-throughput sequencing lab delivers clinical-grade exome data that met their rigorous health and research needs. We made recruitment easy, too: By offering informative, easy-to-use ancestry and traits apps to participants, Helix and the Healthy Nevada Project stimulated demand, enrolling 10,000 Nevadans in less than a week. In less than one year, Healthy Nevada has assembled one of the largest genomic and health data sets in the world.
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Contact us to learn how Helix can enable your population health initiative
A higher standard of care
Helix enables health care providers and research institutions to deliver scalable, low-cost genomic medicine and services to all patients.
Immediate clinical impact
Identify at-risk patients
Population health initiatives help you save lives today. In a health system serving one million people, 30,000 to 40,000 are carrying an ACMG 59 variant—and many aren't aware. 67% of BRCA2 variant carriers have no family history of associated disease.
Support patients
We enable physicians, genetic counselors, and nurses to reach out to consenting participants to deliver positive results and design clinical action plans, including follow-up visits and confirmatory genetic testing.
A lifetime of benefit
Precision medicine on your terms
Add genomics to your workflow at a pace that's right for you. Our flexibility enables precision medicine wherever you need, from pharmacogenomics to carrier screening, rare disease, and risk stratification.
Provide ongoing health updates
With Helix, your patients have all 20,000 genes on file, available to be re-queried throughout their lifetime as your needs and clinical practice evolve. Unlock affordable, on-demand genetic insights across the continuum of care.
“With Helix, we get clinical-grade genomic data and a turnkey platform to enable clinical and research insights, giving us the flexibility to build the initiative that is right for our patients, providers, and researchers. They are fantastic partners in an ambitious population health study.”
Joseph Grzymski, Ph.D.
Principal Investigator, Healthy Nevada ProjectChief Scientific Officer, Renown Health
References
Screen. Research. Discover. Repeat.
Helix’s platform is helping health systems and research institutions accelerate the integration of genomics into clinical care and facilitating novel genetic discovery
Participant recruitment
& engagement
Sequencing &
bioinformatics
Initial return
of results
Sequence once,
query often
Ongoing research
& engagement
Offers your participant an engaging, customized experience
Increase engagement and retention
The Helix platform helps you differentiate your organization in a competitive healthcare marketplace with a human-centric approach to population health:
- Our ancestry and traits insights tap into consumer curiosity, engaging participants and encouraging faster enrollment.
- Raise your profile and drive more interest in your health system with cutting-edge genomics research
- Leverage our flexible model to improve outcomes and raise the general health of the communities you serve.
Helix Exome+ assay
Helix's proprietary Exome+ assay is a panel-grade clinical exome enhanced by ~300,000 informative non-coding regions. Due to its custom design and proprietary bioinformatics solutions, it enables both clinical return of results and supports diverse research applications.
Clinicians and researchers are able to get the benefits of a targeted panel, the breadth of a microarray, and the completeness of an exome—all from one sample and one assay. The discovery and analysis of rare and novel variants, genome-wide imputation, polygenic risk score calculation, ancestry inference, replication and stratification of GWAS findings, and more are all delivered by the Exome+ assay.
- Comprehensive and highly uniform coverage
(>99.5% call rate at ≥20x for clinically relevant regions) - Clinically-validated intragenic and multigenic CNVs (100% sensitivity for ≥2 exons)
- Clinically-validated star allele calls for pharmacogenetic regions (accurate detection of > 100 CYP2D6 star alleles)
- Array-equivalent genome-wide imputation of tens of millions of high-confidence SNPs for discovery and polygenic risk scores
- Inclusion of the full mitochondrial genome